A possible vaccination schedule for the "average" dog is shown below. We do not give a vaccine with Lepto aka Leptospirosis as it has been known to cause issues in the dachshund breed.  

Please view the information below to read about Bordetella aka Kennel Cough. Our dogs being breeding dogs and show dogs get this twice a year.

'Kennel Cough' is the term that was commonly applied to the most prevalent upper respiratory problem in dogs in the United States. Recently, the condition has become known as tracheobronchitis, canine infectious tracheobronchitis, Bordetellosis, or Bordetella. It is highly contagious in dogs. The disease is found worldwide and will infect a very high percentage of dogs in their lifetime.

There are many different agents that can cause of tracheobronchitis. The most common are parainfluenza virus, Bordetella bronchiseptica, and mycoplasma. Canine adenovirus type 2, reovirus, and canine herpes virus are thought to possibly contribute to the disease, as well. Although any one of these organisms can cause symptoms of the disease, the majority of cases are the result of more than one organism.

The most common viral agent is parainfluenza virus. This common virus will cause mild symptoms lasting less than 6 days unless there is involvement of other bacteria, as is usually the case. Most 5-way vaccines and 'kennel cough' vaccines offer some protection against this virus.

Bordetella bronchiseptica is the most common bacteria isolated from dogs with tracheobronchitis. Clinical signs of infections occur 2-14 days after exposure, and if uncomplicated with other agents, symptoms will last around 10 days. However, after the infection has been resolved, the affected animal will continue to shed the bacteria for 6 to 14 weeks and can spread the disease to other susceptible animals during that time. Bordetella is one of the agents protected against through the use of intranasal 'kennel cough' vaccines. Parainfluenza and Bordetella most commonly appear together in infectious tracheobronchitis, creating a disease that normally lasts from 14-20 days.

Treatment

There are two treatment options depending on the severity of the disease. In the most common mild (uncomplicated) form of the disease, antibiotics may or may not be used. Treating the mild case does not shorten the length in which the animal will be a potential spreader of the disease. In addition, bronchodilators like aminophylline or cough suppressants may also be used in treatment of mild cases.

In more severe (complicated) cases where the animal is not eating, running a fever, or showing signs of pneumonia, antibiotics are often used. The most common ones are doxycycline or trimethoprim-sulfa. However, many other choices are also available. Steroids or cough suppressants are not usually recommended because of the risk of immunosuppression with steroids and the need to continue to clear extra fluid or mucous in pneumonia patients. Bronchodilators and even aerosol therapy can be used. In moderate or severe cases, veterinary care should be instituted, as the resultant pneumonia could become life threatening if not treated properly and promptly.

Because pressure on the throat and trachea can make coughing worse, it is recommended that dogs with a cough should wear a head collar or harness instead of a regular neck collar.

Vaccination and prevention

The best prevention is to not expose your dog to other dogs, especially young puppies. If this cannot be avoided, then proper vaccination is the next best option. Chances are that if your dog is regularly vaccinated with a standard 5-way or 7-way vaccine, he is already being protected against several of the agents causing tracheobronchitis, mainly parainfluenza and adenovirus. However, these vaccines alone rarely provide protection against contracting the disease, although they will help reduce the severity of the disease if the animal becomes infected.

There is an injectable Bordatella vaccine, and one that is given intranasally (squirted into the nostrils). Neither vaccine will totally prevent infection with Bordatella. For the injectable vaccine, 2 doses must be given 3-4 weeks apart, and protection does not occur until 1-2 weeks after the second injection.

More commonly, for best protection, an intranasal vaccine containing both parainfluenza and Bordetella is used. Intranasal vaccines create localized immunity that greatly reduces the incidence of clinical signs and illness. The vaccine may be used in puppies as young as 3 weeks of age, only one dose is necessary to provide protection, and protection occurs as early as 3-4 days following vaccination. There are several precautions and warnings that need to be observed pertaining to this vaccine. Some dogs will develop mild signs similar to tracheobronchitis when given this vaccine. Very often, the symptoms will last for several days and the dog will recover without treatment. Dogs that are vaccinated can also shed the virus and cause other dogs to become mildly infected and show mild signs. This shedding usually lasts less than 72 hours. In addition, it takes up to 4 days after vaccination for dogs to develop protection. When you combine these facts, you will see why it is strongly recommend that a dog not be given intranasal vaccine within 72 hours of coming into contact with other susceptible dogs. Do not give the vaccine the day before a dog show, boarding, etc. Try to give at least four days before contact with other dogs and preferably 7 days. This way you will protect your dog from becoming infected by other dogs, and protect those dogs from becoming infected by yours.

In kennels where tracheobronchitis is a problem, strict hygiene with thorough cleaning and disinfection of cages and food and water containers is essential. In addition, kennels that are indoors should have good ventilation with an air turnover rate of at least 12 times an hour. Agents causing tracheobronchitis can be transmitted on hands and clothing as well as through the air, so infected animals must be isolated and handlers should wear gloves and use proper handwashing to help prevent spread. Vaccination of all animals, especially puppies is indicated in problem kennels. After initial vaccination as puppies, a yearly booster is recommended. However, some dogs that are at very high risk are vaccinated every six months.

Human health risk

Until recently, infectious tracheobronchitis was considered to not be a human health risk. Recently however, research indicates that Bordetella bronchiseptica may cause disease in some humans, primarily those with compromised immune systems. In normal, healthy adults there does not appear to be a risk, but young children and immunocompromised individuals should take precautions against coming into contact with animals that have symptoms of tracheobronchitis.

Ref:

Ettinger, S. Textbook of Veterinary Internal Medicine. W.B. Saunders Co. Philadelphia, PA; 1989.

Ford, RB. Bordatella bronchiseptica: Beyond Kennel Cough. In: Bonagura, JD; Twedt, DC (eds.) Current Veterinary Therapy XIV. W.B. Saunders Co. Philadelphia, PA: 2009.

Foster, R; Smith, M. What's the Diagnosis. Macmillan. New York, NY; 1996.

Greene, C. Infectious Diseases of the Dog and Cat. W.B. Saunders Co. Philadelphia, PA; 1998.

Our dogs get this vaccine once a year. Our puppies we keep for show follow the chart above till they are finished with the group of shots. We recomend you talk with your vet about what they suggest for your pup. We have gotten to the point that I use bleach wipes for my shoes to go to petsmart, dog shows, and vet offices. I also clean a lot with bleach water, bleach wipes etc. to try and avoid bringing this home to my babies.

Parvovirus is a very common problem that is a huge killer of puppies. Due to its ability to be transmitted through hands, clothes, and most likely rodents and insects, it is virtually impossible to have a kennel that will not eventually be exposed to the disease. Modified live vaccines are safe and effective, but despite the best vaccination protocol, all puppies will have a window of susceptibility of at least several days where they will be at risk. In addition, the newer CPV-2c strain presents new challenges since it is less detectable in laboratory tests and current vaccines may not be as effective in providing protection against it. Prompt treatment by a veterinarian will increase survivability in infected puppies and working with your veterinarian on a vaccination program that is best for your puppy is important.

Parvovirus is spread through contact with feces containing the virus. The virus is known to survive on inanimate objects - such as clothing, food pans, and cage floors - for 5 months and longer in the right conditions. Insects and rodents may also serve as vectors playing an important role in the transmission of the disease. This means any fecal material or vomit needs to be removed with a detergent before the bleach solution is used. The bleach solution should be used on bedding, dishes, kennel floors and other impervious materials that may be contaminated.

The normal incubation period (time from exposure to the virus to the time when signs of disease appear) is from 7-14 days. Virus can be found in the feces several days before clinical signs of disease appear, and may last for one to two weeks after the onset of the disease.

There is a broad range in the severity of symptoms shown by dogs that are infected with parvovirus. Many adult dogs exposed to the virus show very few, if any, symptoms. The majority of cases of disease are seen in dogs less than 6 months of age with the most severe cases seen in puppies younger than 12 weeks of age. There are also significant differences in response to parvovirus infections and vaccines among different breeds of dogs, with Rottweilers, Doberman Pinschers, and Labrador Retrievers being more susceptible than other breeds.

The most common form of the disease is Parvovirus enteritis is characterized by vomiting (often severe), diarrhea, dehydration, dark or bloody feces, and in severe cases, fever and lowered white blood cell counts. Acute parvovirus enteritis can be seen in dogs of any breed, sex, or age. The disease will progress very rapidly and death can occur as early as two days after the onset of the disease. The presence of gram negative bacteria, parasites, or other viruses can worsen the severity of the disease and slow recovery.

Vaccination

If a puppy recovers from parvovirus infection, he is immune to reinfection for probably at least twenty months and possibly for life. In addition, after recovery the virus is not shed in the feces. There are many commercially prepared attenuated (modified) live CPV-2 vaccines available. The current vaccines protect against all strains of the canine parvovirus, including the relatively new parvovirus-2c strain. Although some people have expressed concern about the possibility of modified live vaccines reverting to a virulent strain after being given and then causing disease, studies have repeatedly shown that this does not occur. Commercially prepared vaccines are safe and do not cause disease.

The primary cause of failure of canine parvovirus vaccines is an interfering level of maternal antibody against the canine parvovirus. Maternal antibodies are the antibodies present in the mother's milk during the first 24 hours after the puppy's birth. The age at which puppies can effectively be immunized is proportional to the titer of the mother and the effectiveness of transfer of maternal antibody within those first 24 hours. High levels of maternal antibodies present in the puppies' bloodstream will block the effectiveness of a vaccine. When the maternal antibodies drop to a low enough level in the puppy, immunization by a commercial vaccine will work. The complicating factor is that there is a period of time from several days to several weeks in which the maternal antibodies are too low to provide protection against the disease, but too high to allow the vaccine to work. This period is called the window of susceptibility. This is the time when despite being vaccinated, a puppy can still contract parvovirus. The length and timing of the window of susceptibility is different in every puppy in every litter.

Canine distemper is a contagious, incurable, often fatal, multisystemic viral disease that affects the respiratory, gastrointestinal, and central nervous systems. Distemper is caused by the canine distemper virus (CDV).

Incidence
Canine distemper occurs worldwide, and once was the leading cause of death in unvaccinated puppies. Widespread vaccination programs have dramatically reduced its incidence.

CDV occurs among domestic dogs and many other carnivores, including raccoons, skunks, and foxes. CDV is fairly common in wildlife. The development of a vaccine in the early 1960s led to a dramatic reduction in the number of infected domestic dogs. It tends to occur now only as sporadic outbreaks.

Young puppies between 3 and 6 months old are most susceptible to infection and disease and are more likely to die than infected adults. Nonimmunized older dogs are also highly susceptible to infection and disease. Nonimmunized dogs that have contact with other nonimmunized dogs or with wild carnivores have a greater risk of developing canine distemper.

Prevention
The best prevention against canine distemper is vaccination. Vaccination works well even in animals that have already been exposed to the virus, if it is administered within 4 days of exposure. Exposure to CDV via vaccination induces long lasting, but not permanent, immunity. Dogs should receive annual vaccinations to ensure protection.

There are several different types of distemper vaccines available, each with advantages and disadvantages. Pet owners should discuss the various options with their veterinarians. The two most common vaccines are canine tissue culture-adapted vaccines and chick embryo-adapted vaccines.

Canine tissue culture-adapted vaccines (e.g., Rockborn strain) are nearly 100% effective; they can very rarely cause fatal encephalitis (swelling of the brain) 1 to 2 weeks after vaccination. This type of vaccine is especially risky in dogs with weakened immune systems.

Chick embryo adapted-vaccines (e.g., Onderstepoort and Lederle strain) are safer than the Rockborn strain but are only about 80% effective.

Most puppies are born with their mother's antibodies to CDV, which prevents them from becoming infected if exposed to the virus. They begin to lose their maternal protection between 6 and 12 weeks of age, which is when puppies should be vaccinated. Two to three vaccinations should be administered during this period. Dogs should be revaccinated yearly thereafter.

Multidog households
Any dog that is suspected of being infected should be isolated from other dogs. Other dogs should be vaccinated, if they haven't already been.

CDV doesn't last long outside the dog's body; heat, sunlight, most detergents, soaps, and various chemicals inactivate it. After an infected dog has been removed from the premises, contaminated objects and living areas should be disinfected with a 1:30 bleach-water solution.

The initial symptom is fever (103°F to 106°F), which usually peaks 3 to 6 days after infection. The fever often goes unnoticed and may peak again a few days later. Dogs may experience eye and nose discharge, depression, and loss of appetite (anorexia). After the fever, symptoms vary considerably, depending on the strain of the virus and the dog's immunity.

Many dogs experience gastrointestinal and respiratory symptoms, such as:

• Conjunctivitis (discharge from the eye)
• Diarrhea
• Fever (usually present but unnoticed)
• Pneumonia (cough, labored breathing)
• Rhinitis (runny nose)
• Vomiting

These symptoms are often exacerbated by secondary bacterial infections. Dogs almost always develop encephalomyelitis (an inflammation of the brain and spinal cord), the symptoms of which are variable and progressive. Most dogs that die from distemper, die from neurological complications such as the following:

• Ataxia (muscle incoordination)
• Depression
• Hyperesthesia (increased sensitivity to sensory stimuli, such as pain or touch)
• Myoclonus (muscle twitching or spasm), which can become disabling
• Paralysis
• Paresis (partial or incomplete paralysis)
• Progressive deterioration of mental abilities
• Progressive deterioration of motor skills
• Seizures that can affect any part of the body (One type of seizure that affects the head, and is unique to distemper, is sometimes referred to as a "chewing gum fit" because the dog appears to be chewing gum.)

Many dogs experience symptoms of the eye:

• Inflammation of the eye (either keratoconjunctivitis, inflammation of the cornea and conjunctiva, or chorioretinitis, inflammation of the choroid and retina)
• Lesions on the retina (the innermost layer of the eye)
• Optic neuritis (inflammation of the optic nerve which leads to blindness)

Two relatively minor conditions that often become chronic, even in dogs that recover are:

• Enamel hypoplasia (unenameled teeth that erode quickly in puppies whose permanent teeth haven't erupted yet—the virus kills all the cells that make teeth enamel)
• Hyperkeratosis (hardening of the foot pads and nose)

In utero infection of fetuses is rare, but can happen. This can lead to spontaneous abortion, persistent infection in newborn puppies, or the birth of normal looking puppies that rapidly develop symptoms and die within 4 to 6 weeks.

Since there's no cure for distemper, treatment is supportive.

• Provide a clean, warm, draft-free environment.
• Keep eyes and nose clear of discharge.
• Give antiemetics (anti-nausea and anti-vomiting drugs) if there is vomiting.
• Give antidiarrheals for diarrhea.
• Monitor closely for dehydration. Dogs without an appetite that are experiencing vomiting and diarrhea may require intravenous rehydration therapy.
• Antibiotics or bronchodilators are prescribed for pneumonia.
• Anticonvulsants may partially control seizures. Many veterinarians prescribe them before seizures start.
• Myoclonus is untreatable (and irreversible).
• Puppies who recover but have hypoplasia (unenameled teeth that erode quickly) can have the enamel restored to prevent further tooth decay.
• Glucocorticoid therapy can sometimes help blindness due to optic neuritis (inflammation of the optic nerve). This may help in the short term, but glucocorticoids weaken the immune system and may make symptoms worse. Diagnosis can be difficult and is based on the dog's vaccination history, clinical symptoms, and laboratory tests.

Blood tests usually are not helpful in the diagnosis, though in some cases they may reveal lymphopenia (a deficiency of lymphocytes, a type of immune system cell) during early infection, followed by leukocytosis (an increase in the number of white blood cells circulating through the blood) during later infection.

Imaging studies (e.g., x-rays, CT scans) can diagnose pneumonia.

Inclusion bodies (unique cellular structures that indicate the presence of the virus) can be detected with microscopic examination of buffy coat cells (cells that make up the "buffy layer" of centrifuged blood) and conjunctival secretions (secretions from the conjunctiva, the inner lining of the eyelids). A negative result does not rule out the possibility that the dog has distemper.

An immunofluorescent assay can detect viral antigens (proteins that the immune system manufactures to fight the virus) in the buffy coat cells and conjunctival secretions when inclusion bodies are not visible. Immunofluorescence involves using special proteins labeled with a fluorescent chemical that bind to the antigens and make them visible. Again, a negative result does not rule out the possibility that the dog has distemper.

Polymerase chain reaction (PCR), a technique that helps identify the virus's genetic material, is usually more sensitive than either microscopic examination for viral inclusions or immunofluorescence. It can be a difficult procedure and it is not always successful.

Cerebrospinal fluid (CSF) can be examined for CDV-specific antibodies and elevated levels of particular proteins and cells that indicate the presence of the virus.

Differential Diagnosis
Many diseases can cause symptoms resembling canine distemper and should be ruled out during diagnosis. Respiratory symptoms (e.g., cough and labored breathing) could be caused by bacterial pneumonia. Intestinal symptoms (e.g., vomiting and diarrhea) could be caused by gastroenteritis (an inflammatory bowel disease). Seizures and other neurological symptoms could be caused by toxoplasmosis (a protozoan infection) or epilepsy.

http://www.animalhealthchannel.com/distemper/index.shtml